Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741996 | 0.77 | GAA (0.41) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| SCHEMBL9744587 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| SCHEMBL9744511 | 0.69 | MAPT (0.40) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| Hydrochloric Acid SCHEMBL9741041 | 0.68 | KDM4E (0.38) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| SCHEMBL9745897 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| SCHEMBL9746051 | 0.67 | KDM4E (0.41) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| Hydrochloric Acid SCHEMBL9741412 | 0.65 | POLB (0.37) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| SCHEMBL9875866 | 0.62 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| SCHEMBL9744469 | 0.62 | BLM (0.41) | KDM4EALDH1A1GAAMAPK1NSD2 | |
| SCHEMBL9740597 | 0.59 | BLM (0.45) | KDM4EALDH1A1GAAMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112968-A | Monobactam hydrazide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-05-12 | — | — | US | claimed |
| US-5112968-A | Monobactam hydrazide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-05-12 | — | — | US | disclosed |