Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9741462 | 0.84 | PLA2G7 (0.31) | PLA2G7 | |
| SCHEMBL9740438 | 0.81 | BLM (0.45) | KDM4EALDH1A1GAAMAPK1BLM | |
| SCHEMBL9744469 | 0.80 | BLM (0.41) | KDM4EALDH1A1GAAMAPK1ALPL | |
| SCHEMBL9744587 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1GAAMAPK1ALPL | |
| SCHEMBL9741996 | 0.77 | GAA (0.41) | KDM4EALDH1A1GAAMAPK1ALPL | |
| SCHEMBL9746051 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1GAAMAPK1ALPL | |
| SCHEMBL9744511 | 0.74 | MAPT (0.40) | KDM4EALDH1A1GAAMAPK1ALPL | |
| Hydrochloric Acid SCHEMBL9741412 | 0.70 | POLB (0.37) | KDM4EALDH1A1GAAMAPK1ALPL | |
| SCHEMBL9744935 | 0.68 | KDM4E (0.35) | KDM4EALDH1A1GAAMAPK1ALPL | |
| Hydrochloric Acid SCHEMBL9741041 | 0.68 | KDM4E (0.38) | KDM4EALDH1A1GAAMAPK1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112968-A | Monobactam hydrazide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-05-12 | — | — | US | disclosed |