Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198161 | 0.93 | KMT2A (0.64) | KMT2AMAPK1HSD17B10ALDH1A1MEN1 | |
| SCHEMBL9203711 | 0.87 | MAPK1 (0.67) | KMT2AMAPK1HSD17B10MEN1POLB | |
| SCHEMBL9203357 | 0.84 | MAPK1 (0.63) | KMT2AMAPK1HSD17B10MEN1POLB | |
| SCHEMBL9442138 | 0.82 | MAPK1 (0.74) | KMT2AMAPK1HSD17B10MEN1POLB | |
| SCHEMBL9196878 | 0.82 | MAPK1 (0.52) | KMT2AMAPK1HSD17B10MEN1POLB | |
| SCHEMBL15094425 | 0.79 | RAB9A (0.59) | KMT2AMAPK1HSD17B10ALDH1A1MEN1 | |
| SCHEMBL9200225 | 0.77 | MAPK1 (0.50) | KMT2AMAPK1HSD17B10MEN1POLB | |
| Carboxin SCHEMBL18392 | 0.76 | MAPK1 (1.00) | KMT2AMAPK1HSD17B10MEN1POLB | |
| Carboxin SCHEMBL8819780 | 0.76 | MAPK1 (1.00) | KMT2AMAPK1HSD17B10MEN1POLB | |
| SCHEMBL9198342 | 0.76 | KMT2A (0.70) | KMT2AMAPK1HSD17B10MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | claimed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | claimed |