SCHEMBL9745250

SCHEMBL9745250

CCCCCCCCCCCCC(SC)C1=CC(=O)OC1O

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDCD4 Q53EL6 7/20 0.41
DAGLA Q9Y4D2 1/20 0.35
FDPS P14324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7296014 0.82 PDCD4 (0.47) PDCD4DAGLA
SCHEMBL9422969 0.80 PDCD4 (0.42) PDCD4DAGLAFDPS
SCHEMBL9745274 0.78 PDCD4 (0.39) PDCD4DAGLA
SCHEMBL9325205 0.78 PDCD4 (0.41) PDCD4DAGLA
SCHEMBL9746833 0.77 PDCD4 (0.40) PDCD4DAGLAFDPS
SCHEMBL9767030 0.76 PDCD4 (0.39) PDCD4DAGLA
SCHEMBL9745710 0.76 PDCD4 (0.39) PDCD4DAGLA
SCHEMBL9767002 0.76 GPR84 (0.42) PDCD4
SCHEMBL8985089 0.76 PDCD4 (0.40) PDCD4
SCHEMBL9325018 0.76 PDCD4 (0.40) PDCD4DAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089485-A ANTI-INFLAMMATORY FURANONES ALLERGAN, INC. (US) 1992-02-18 US disclosed
EP-0369811-A2 Anti-inflammatory furanones ALLERGAN, INC (US) 1990-05-23 EP disclosed