Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | PDCD4 | Q53EL6 | 8/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767030 | 0.90 | PDCD4 (0.39) | PDCD4 | |
| SCHEMBL9766890 | 0.85 | FAAH (0.37) | PDCD4 | |
| SCHEMBL9767329 | 0.81 | PDCD4 (0.39) | PDCD4 | |
| SCHEMBL9766912 | 0.81 | PDCD4 (0.39) | PDCD4 | |
| SCHEMBL7296014 | 0.80 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9422969 | 0.78 | PDCD4 (0.42) | PDCD4 | |
| SCHEMBL9746833 | 0.77 | PDCD4 (0.40) | PDCD4 | |
| SCHEMBL14339054 | 0.75 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9671381 | 0.75 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL8985076 | 0.75 | PDCD4 (0.47) | PDCD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013850-A | 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents | ALLERGAN, INC. (US) | 1991-05-07 | — | — | US | disclosed |