Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506410 | 0.89 | ALDH1A1 (0.48) | CYP2C9ALDH1A1NPSR1TSHRMAPT | |
| SCHEMBL9502467 | 0.89 | MEN1 (0.52) | CYP2C9ALDH1A1NPSR1TSHRMAPT | |
| SCHEMBL9745520 | 0.81 | CYP2C9 (0.49) | CYP2C9ALDH1A1NPSR1TSHRMAPT | |
| SCHEMBL10709806 | 0.79 | ALDH1A1 (0.44) | CYP2C9ALDH1A1NPSR1TSHRMAPT | |
| SCHEMBL10553486 | 0.79 | GSTP1 (0.52) | CYP2C9ALDH1A1NPSR1TSHRMAPT | |
| SCHEMBL9746104 | 0.77 | L3MBTL1 (0.39) | ALDH1A1NPSR1MAPTMEN1LMNA | |
| SCHEMBL9844351 | 0.77 | MEN1 (0.47) | CYP2C9ALDH1A1NPSR1TSHRMAPT | |
| SCHEMBL10552842 | 0.76 | L3MBTL1 (0.42) | ALDH1A1NPSR1MAPTTP53HTT | |
| SCHEMBL9746083 | 0.75 | HTT (0.55) | CYP2C9ALDH1A1NPSR1TSHRMAPT | |
| SCHEMBL10553919 | 0.74 | TSHR (0.51) | CYP2C9ALDH1A1NPSR1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268800-B1 | PHENOXYACETIC ACID DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4853404-A | DIURETIS, SALURETICS, URICOSURETICS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-01 | — | — | US | disclosed |