Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944714 | 1.00 | HMGCR (0.40) | HMGCR | |
| SCHEMBL6944933 | 0.89 | HMGCR (0.41) | HMGCR | |
| SCHEMBL6944927 | 0.89 | HMGCR (0.41) | HMGCR | |
| SCHEMBL6949271 | 0.85 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9441753 | 0.85 | ALDH1A1 (0.32) | HMGCR | |
| SCHEMBL6944852 | 0.81 | HMGCR (0.41) | HMGCR | |
| SCHEMBL10442012 | 0.80 | HMGCR (0.41) | HMGCR | |
| SCHEMBL8953082 | 0.80 | — | — | |
| SCHEMBL9562779 | 0.79 | — | — | |
| SCHEMBL8952973 | 0.79 | HMGCR (0.49) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091378-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-02-25 | — | — | US | disclosed |