Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.68 |
| ▸ | NPC1 | O15118 | 10/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476873 | 0.86 | RAB9A (0.80) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8604284 | 0.85 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9196939 | 0.84 | SMN1; SMN2 (0.61) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29666364 | 0.83 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL7176133 | 0.83 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8655203 | 0.82 | KDM4E (0.54) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8748351 | 0.82 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL30780905 | 0.81 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL1592859 | 0.81 | KDM4E (0.53) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL1592318 | 0.81 | KDM4E (0.53) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | claimed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | claimed |
| CN-1051036-A | The treatment of HIV (human immunodeficiency virus) infections and in treatment used compound | UNIROYAL CHEM CO INC (US) | 1991-05-01 | — | — | CN | claimed |