Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745628 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNANPSR1MAPTHDAC4 | |
| SCHEMBL9745446 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNANPSR1MAPTHDAC4 | |
| SCHEMBL27415403 | 0.85 | ALDH1A1 (0.46) | ALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL16055833 | 0.85 | ALDH1A1 (0.46) | ALDH1A1LMNANPSR1 | |
| SCHEMBL27415402 | 0.85 | ALDH1A1 (0.46) | ALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL27492313 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNANPSR1GAAKDM4E | |
| SCHEMBL27492314 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNANPSR1GAAKDM4E | |
| SCHEMBL8744093 | 0.82 | ALDH1A1 (0.60) | ALDH1A1LMNANPSR1SMN1; SMN2KDM4E | |
| SCHEMBL6768435 | 0.79 | NPSR1 (0.57) | ALDH1A1LMNANPSR1MAPTGAA | |
| SCHEMBL27509442 | 0.79 | TDP1 (0.48) | ALDH1A1LMNAMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |