⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989992 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL5005255 | 0.71 | — | — | |
| SCHEMBL5005529 | 0.71 | — | — | |
| Water SCHEMBL10550372 | 0.69 | ALDH1A1 (0.32) | — | |
| Ethylamine SCHEMBL3178087 | 0.69 | CYP2D6 (0.32) | — | |
| Bromoethane SCHEMBL4028485 | 0.69 | ALDH1A1 (0.40) | — | |
| SCHEMBL566706 | 0.68 | — | — | |
| SCHEMBL3626203 | 0.68 | — | — | |
| SCHEMBL29146 | 0.68 | — | — | |
| SCHEMBL5683569 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148587-B1 | CARBONITRILE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | PFIZER (US) | 2021-02-24 | — | — | EP | disclosed |
| US-10328082-B2 | Methods of use and combinations | PFIZER INC. (US) | 2019-06-25 | — | — | US | disclosed |
| US-20170252352-A1 | METHODS OF USE AND COMBINATIONS | PFIZER INC. (US) | 2017-09-07 | — | — | US | disclosed |
| EP-2925725-B1 | NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS | PFIZER (US) | 2016-11-09 | — | — | EP | disclosed |
| US-9328104-B2 | Selective androgen receptor modulators | PFIZER INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-20140155390-A1 | NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS | PFIZER INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |