Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 13/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745713 | 0.90 | KDM4E (0.49) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL9746049 | 0.88 | POLB (0.46) | KDM4ESMN1; SMN2POLBARMEN1 | |
| SCHEMBL9748856 | 0.88 | KDM4E (0.44) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL9745883 | 0.87 | KDM4E (0.50) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL9745956 | 0.86 | KDM4E (0.45) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL30997471 | 0.81 | POLB (0.63) | POLBGAAARSCN9AMAPK14 | |
| SCHEMBL1374637 | 0.80 | KDM4E (0.48) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL9746465 | 0.80 | POLB (0.49) | KDM4ESMN1; SMN2POLBARMEN1 | |
| SCHEMBL9746042 | 0.79 | SMN1; SMN2 (0.43) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL9746156 | 0.79 | VEGFA (0.44) | KDM4ESMN1; SMN2POLBGAAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118431-A | Phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5061388-A | Novel phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |