Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745713 | 0.87 | KDM4E (0.49) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL10084168 | 0.86 | AR (0.45) | SMN1; SMN2POLBGAAARMEN1 | |
| SCHEMBL10084200 | 0.84 | TLR8 (0.51) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL8466143 | 0.84 | MAPT (0.41) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL12780794 | 0.84 | ESR1 (0.50) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL29800655 | 0.84 | POLB (0.51) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL7121279 | 0.84 | POLB (0.51) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL1374728 | 0.82 | SMN1; SMN2 (0.50) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL9359794 | 0.82 | KDM4E (0.54) | KDM4ESMN1; SMN2POLBGAAAR | |
| SCHEMBL17808966 | 0.81 | AR (0.44) | SMN1; SMN2POLBGAAARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452959-B2 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-11-18 | — | — | US | claimed |
| EP-1507816-A4 | OLIGOMERIC HYDROXY ARYLETHER PHTHALONITILES AND SYNTHESIS THEREOF | US GOV SEC NAVY (US) | 2006-05-31 | — | — | EP | claimed |
| EP-1507816-A1 | OLIGOMERIC HYDROXY ARYLETHER PHTHALONITILES AND SYNTHESIS THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (US) | 2005-02-23 | — | — | EP | claimed |
| US-20040181029-A1 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY, THE | 2004-09-16 | — | — | US | claimed |
| US-20040181027-A1 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | NAVY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2004-09-16 | — | — | US | claimed |
| US-20040181028-A1 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | NAVY, THE, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2004-09-16 | — | — | US | claimed |
| US-20030229198-A1 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | NAVY, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF, THE | 2003-12-11 | — | — | US | claimed |
| WO-2003091312-A1 | OLIGOMERIC HYDROXY ARYLETHER PHTHALONITILES AND SYNTHESIS THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRSENTED BY THE SECRETARY OF THE NAVY (US) | 2003-11-06 | — | — | WO | claimed |
| US-8530607-B2 | Aromatic ether and alkynyl containing phthalonitriles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-09-10 | — | — | US | disclosed |
| US-20110288254-A1 | AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110263775-A1 | PHOSPHINE OXIDE CONTAINING PHTHALONITRILES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2011-10-27 | — | — | US | disclosed |
| US-8039576-B2 | Aromatic ether and alkynyl containing phthalonitriles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2011-10-18 | — | — | US | disclosed |
| US-7511113-B2 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-03-31 | — | — | US | disclosed |
| US-20090069484-A1 | AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES | THE GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-03-12 | — | — | US | disclosed |
| US-20040181029-A1 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY, THE | 2004-09-16 | — | — | US | disclosed |
| US-20040181027-A1 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | NAVY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2004-09-16 | — | — | US | disclosed |
| US-20040181028-A1 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | NAVY, THE, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2004-09-16 | — | — | US | disclosed |
| US-6756470-B2 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2004-06-29 | — | — | US | disclosed |
| US-20030229198-A1 | Oligomeric hydroxy arylether phthalonitiles and synthesis thereof | NAVY, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF, THE | 2003-12-11 | — | — | US | disclosed |
| WO-2003091312-A1 | OLIGOMERIC HYDROXY ARYLETHER PHTHALONITILES AND SYNTHESIS THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRSENTED BY THE SECRETARY OF THE NAVY (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288254-A1 | AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES | PNN, BECN1, ACIN1 | KDM4E 675/4885SMN1; SMN2 1799/4885POLB 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.