Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258758 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBCYP2C9TP53USP2 | |
| SCHEMBL20714306 | 0.76 | AOC3 (0.50) | SMN1; SMN2POLBTP53USP2MAPK1 | |
| SCHEMBL4415031 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBCYP1A2MAPK1TSHR | |
| Propionic Acid SCHEMBL10593320 | 0.74 | POLB (0.64) | SMN1; SMN2POLBCYP2C9CYP1A2MAPK1 | |
| SCHEMBL9078674 | 0.74 | AOC3 (0.48) | SMN1; SMN2POLBCYP2C9TP53MAPK1 | |
| SCHEMBL6507597 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBCYP2C9TP53MAPK1 | |
| SCHEMBL22231486 | 0.72 | AOC3 (0.47) | SMN1; SMN2POLBCYP1A2MAPK1TSHR | |
| SCHEMBL9079266 | 0.72 | AOC3 (0.47) | SMN1; SMN2POLBTP53MAPK1TSHR | |
| SCHEMBL6601841 | 0.72 | AOC3 (0.47) | SMN1; SMN2POLBCYP2C9MAPK1TSHR | |
| SCHEMBL6601376 | 0.72 | AOC3 (0.50) | SMN1; SMN2POLBMAPK1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128448-A | Peptide hormones | HOFFMAN-LA ROCHE INC. (US) | 1992-07-07 | — | — | US | disclosed |