Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9078674 | 0.84 | AOC3 (0.48) | SMN1; SMN2LMNAAOC3NPC1RAB9A | |
| SCHEMBL6601376 | 0.82 | AOC3 (0.50) | SMN1; SMN2LMNAAOC3NPC1RAB9A | |
| SCHEMBL20714306 | 0.82 | AOC3 (0.50) | SMN1; SMN2LMNAAOC3NPC1RAB9A | |
| SCHEMBL9079266 | 0.82 | AOC3 (0.47) | SMN1; SMN2LMNAAOC3NPC1RAB9A | |
| SCHEMBL6601841 | 0.82 | AOC3 (0.47) | SMN1; SMN2LMNAAOC3NPC1RAB9A | |
| SCHEMBL22231486 | 0.82 | AOC3 (0.47) | SMN1; SMN2LMNAAOC3NPC1RAB9A | |
| SCHEMBL7390849 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAAOC3NPC1RAB9A | |
| SCHEMBL4415031 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2AOC3NPC1RAB9APOLB | |
| SCHEMBL21889509 | 0.79 | LTA4H (0.55) | SMN1; SMN2LMNAAOC3NPC1RAB9A | |
| SCHEMBL4638106 | 0.79 | AOC3 (0.44) | SMN1; SMN2LMNAAOC3RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107456-A1 | Substituted pyrazolines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2005-05-19 | — | — | US | disclosed |
| EP-1467971-A1 | SUBSTITUTED PYRAZOLINES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003059887-A1 | SUBSTITUTED PYRAZOLINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107456-A1 | Substituted pyrazolines for use as pesticides | DDT, ACHE, CHRM1 | SMN1; SMN2 2827/4885LMNA 4513/4885AOC3 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.