SCHEMBL9745758

SCHEMBL9745758

C=C(C(=O)OC)C(Cl)(Cl)Cl

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
L3MBTL1 Q9Y468 1/20 0.41
TET2 Q6N021 1/20 0.34
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
GPR35 Q9HC97 1/20 0.32
MAPT P10636 1/20 0.31
EGLN1 Q9GZT9 1/20 0.30
CYP2C19 P33261 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9745788 0.84 ALDH1A1 (0.48) ALDH1A1L3MBTL1TET2GPR35MAPT
SCHEMBL9746339 0.77 ALDH1A1 (0.41) ALDH1A1L3MBTL1TET2MAPTEGLN1
SCHEMBL1899520 0.76 ALDH1A1 (0.50) ALDH1A1TET2EGLN1
SCHEMBL11365748 0.75 DGAT1 (0.33) ALDH1A1L3MBTL1TSHR
SCHEMBL28123063 0.75 ALDH1A1 (0.39) ALDH1A1L3MBTL1TET2MAPT
Carbon Tetrachloride SCHEMBL10935882 0.74 ALDH1A1 (0.79) ALDH1A1L3MBTL1TET2TSHRMAPT
SCHEMBL219777 0.74 ALDH1A1 (0.48) ALDH1A1TET2GPR35MAPTEGLN1
SCHEMBL9747397 0.74 ALDH1A1 (0.48) ALDH1A1TET2GPR35EGLN1
SCHEMBL9745781 0.74 ALDH1A1 (0.48) ALDH1A1TET2GPR35EGLN1
SCHEMBL16881862 0.74 ALDH1A1 (0.48) ALDH1A1TET2TSHREGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed