SCHEMBL9745800

SCHEMBL9745800

CCC[Si](Cl)(c1ccccc1)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
TP53 P04637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
TAAR1 Q96RJ0 2/20 0.30
SLC6A2 P23975 1/20 0.30
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9746360 0.83 TP53 (0.33) TP53ALDH1A1GAATAAR1SLC6A2
SCHEMBL705990 0.76 TP53 (0.35) NR1H2NR1H3TP53KDM4EALDH1A1
SCHEMBL707143 0.76 TP53 (0.35) NR1H2NR1H3TP53KDM4EALDH1A1
SCHEMBL704073 0.76 TP53 (0.35) NR1H2NR1H3TP53KDM4EALDH1A1
SCHEMBL6580976 0.74 POLB (0.34) ALDH1A1
SCHEMBL1313499 0.74 ESR1 (0.35) TP53KDM4EALDH1A1GAAHPGD
SCHEMBL9746718 0.73 NR1H2 (0.34) NR1H2NR1H3TP53ALDH1A1GAA
SCHEMBL2271815 0.73 SMN1; SMN2 (0.32) TP53
SCHEMBL2266530 0.72 TP53 (0.32) TP53KDM4EALDH1A1GAAHPGD
SCHEMBL21383027 0.72 TP53 (0.32) TP53KDM4EALDH1A1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed