Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622811 | 0.85 | TDP1 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19180885 | 0.85 | SIGMAR1 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28239435 | 0.82 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4494444 | 0.82 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23532521 | 0.79 | SIGMAR1 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19755160 | 0.79 | ESR1 (0.56) | SLC6A3SIGMAR1TDP1L3MBTL1HTR3A | |
| SCHEMBL5804123 | 0.79 | ADRA1A (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15735638 | 0.77 | TAAR1 (0.46) | MAPTMAOBNPC1RAB9AGAA | |
| SCHEMBL28958133 | 0.77 | CHRM2 (0.48) | ADRA1ASLC6A3SIGMAR1MAOAL3MBTL1 | |
| SCHEMBL4058177 | 0.77 | IDO1 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099006-A | ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates | RHONE-POULENC INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0319384-A2 | Cerium hydrocarbonsilyloxydes and process for their manufacture | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319383-A2 | Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |