Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417993 | 0.90 | LTA4H (0.38) | LTA4HPCSK9TSHRTDP1PTGS2 | |
| SCHEMBL9748153 | 0.88 | TP53 (0.31) | — | |
| SCHEMBL8992243 | 0.84 | LTA4H (0.36) | LTA4HPCSK9TSHRTDP1PTGS2 | |
| SCHEMBL418320 | 0.84 | LTA4H (0.38) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL8992383 | 0.82 | DNM1 (0.40) | LTA4HCES2CES1SMN1; SMN2SIGMAR1 | |
| SCHEMBL418037 | 0.82 | DNM1 (0.40) | LTA4HCES2CES1SMN1; SMN2SIGMAR1 | |
| SCHEMBL415279 | 0.82 | DNM1 (0.40) | LTA4HCES2CES1SMN1; SMN2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27521289 | 0.77 | TLR8 (0.34) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL417806 | 0.77 | TP53 (0.38) | LTA4HPCSK9TSHRPTGS2CES2 | |
| SCHEMBL114778 | 0.73 | LTA4H (0.38) | LTA4HPCSK9TSHRTDP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |