Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433163 | 0.79 | ESR2 (0.56) | VCAM1ALDH1A1LMNAIKBKBKDR | |
| SCHEMBL8140554 | 0.79 | VCAM1 (0.60) | VCAM1ALDH1A1LMNAAPPIKBKB | |
| SCHEMBL11020287 | 0.78 | HSD17B10 (0.42) | VCAM1ALDH1A1LMNAAPPMEN1 | |
| SCHEMBL7679539 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNAAPPMEN1KMT2A | |
| SCHEMBL27208732 | 0.78 | CA12 (0.42) | ALDH1A1LMNAAPPMEN1KMT2A | |
| SCHEMBL6799885 | 0.77 | ESR2 (0.38) | — | |
| SCHEMBL11409143 | 0.76 | POLB (0.49) | ALDH1A1LMNAMEN1KMT2ACES1 | |
| SCHEMBL3788758 | 0.75 | APP (0.39) | ALDH1A1LMNAAPPMEN1KMT2A | |
| SCHEMBL731049 | 0.74 | ESR2 (0.44) | ALDH1A1CYP1A2CYP2C19HPGDTDP1 | |
| SCHEMBL11287223 | 0.74 | AR (0.39) | ALDH1A1LMNAAPPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159040-A | Neutral and electrically conductive poly(heterocyclic vinylenes) and processes for preparing same | ALLIED-SIGNAL INC. (US) | 1992-10-27 | — | — | US | disclosed |
| US-5068060-A | Neutral and electrically conductive poly(heterocyclic vinylenes) and processes for preparing same | ALLIED-SIGNAL INC. (US) | 1991-11-26 | — | — | US | disclosed |
| WO-1991015534-A1 | ELECTRICALLY CONDUCTIVE POLY(AROMATIC VINYLENES) AND POLY(HETEROAROMATIC VINYLENES) | ALLIED-SIGNAL INC. (US) | 1991-10-17 | — | — | WO | disclosed |
| US-4900782-A | Stabilized polyelectrolyte precursors of poly(aromatic and heteroaromatic vinylenes) | ALLIED-SIGNAL INC. (US) | 1990-02-13 | — | — | US | disclosed |