Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832222 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TP53TDP1MEN1LMNA | |
| SCHEMBL9104204 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TP53TDP1MEN1LMNA | |
| SCHEMBL3362751 | 0.98 | TDP1 (0.40) | ALDH1A1TP53TDP1MEN1LMNA | |
| SCHEMBL1169909 | 0.93 | TDP1 (0.41) | ALDH1A1TP53TDP1MEN1LMNA | |
| SCHEMBL4091793 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TP53TDP1MEN1LMNA | |
| SCHEMBL303151 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TP53THRBKCNH2NPC1 | |
| SCHEMBL10623984 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TP53THRBKCNH2NPC1 | |
| SCHEMBL10628695 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TP53THRBKCNH2NPC1 | |
| SCHEMBL10628487 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TP53THRBKCNH2NPC1 | |
| SCHEMBL3359315 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TP53LMNAKCNH2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313474-B1 | AN OPTICAL ARTICLE EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0313474-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4792208-A | POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR | EASTMAN KODAK COMPANY (US) | 1988-12-20 | — | — | US | disclosed |