SCHEMBL9746136

SCHEMBL9746136

O=C([O-])C(C(=O)[O-])=C1SCCS1.[Ba+2]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
MCL1 Q07820 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 2/20 0.33
KLKB1 P03952 1/20 0.32
CTSB P07858 1/20 0.32
ELANE P08246 1/20 0.32
CTRB1 P17538 1/20 0.32
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9746700 0.97 KDM4E (0.34) KDM4ESMN1; SMN2NPC1MEN1ALDH1A1
SCHEMBL1685875 0.72 ALDH1A1 (0.43) KDM4ESMN1; SMN2NPC1MEN1ALDH1A1
SCHEMBL9744386 0.70 ALDH1A1 (0.42) KDM4ESMN1; SMN2NPC1MEN1ALDH1A1
SCHEMBL9745475 0.68 ADRA1A (0.43)
Water SCHEMBL9745425 0.67 ADRA1A (0.42)
SCHEMBL12574011 0.57
Bicarbonate SCHEMBL9100985 0.57 CA4 (0.60) MEN1KMT2ALMNA
Oxalic Acid SCHEMBL48147 0.57
Bicarbonate SCHEMBL59358 0.54
Oxalic Acid SCHEMBL1786041 0.54 CA4 (0.70) MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142075-A Anti-tumor platinum(II) complexes and process for the preparation thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1992-08-25 US disclosed