Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14453840 | 0.73 | RIPK1 (0.33) | NR1H2NR1H3ESR1ESR2AOC3 | |
| SCHEMBL272814 | 0.72 | NR1H2 (0.39) | NR1H2NR1H3ESR1ESR2AOC3 | |
| SCHEMBL564255 | 0.72 | NR1H2 (0.39) | NR1H2NR1H3ESR1ESR2AOC3 | |
| SCHEMBL273497 | 0.72 | ESR1 (0.39) | NR1H2NR1H3ESR1ESR2ALOX5 | |
| SCHEMBL2021132 | 0.72 | ESR1 (0.39) | NR1H2NR1H3ESR1ESR2ALOX5 | |
| SCHEMBL152027 | 0.72 | NR1H2 (0.39) | NR1H2NR1H3ESR1ESR2AOC3 | |
| SCHEMBL271794 | 0.72 | ESR1 (0.39) | NR1H2NR1H3ESR1ESR2ALOX5 | |
| Water SCHEMBL3812783 | 0.70 | NR1H2 (0.38) | NR1H2NR1H3ESR1ESR2AOC3 | |
| SCHEMBL272396 | 0.70 | ESR1 (0.43) | NR1H2NR1H3ESR1ESR2AOC3 | |
| SCHEMBL273488 | 0.70 | ESR1 (0.43) | NR1H2NR1H3ESR1ESR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |