SCHEMBL3481875

SCHEMBL3481875

CCCC[Si](Cl)(CC)CC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270148 0.94 TSHR (0.35) TSHRLMNATDP1THRBALDH1A1
SCHEMBL9746242 0.91 TSHR (0.39) TSHRLMNATDP1THRBALDH1A1
SCHEMBL2272086 0.88 TSHR (0.32) TSHRLMNATDP1THRB
SCHEMBL12504455 0.88 TSHR (0.44) TSHRLMNATHRBALDH1A1
SCHEMBL7691169 0.88 TSHR (0.44) TSHRLMNATHRBALDH1A1
SCHEMBL8527206 0.88 TSHR (0.44) TSHRLMNATHRBALDH1A1
SCHEMBL28309952 0.88 TSHR (0.44) TSHRLMNATHRBALDH1A1
SCHEMBL12504372 0.88 TSHR (0.44) TSHRLMNATHRBALDH1A1
SCHEMBL8926895 0.88 TSHR (0.44) TSHRLMNATHRBALDH1A1
SCHEMBL707199 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118831596-A Hydrophobically modified ethylene oxychlorination catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-10-25 CN claimed
CN-101007821-A Fluorescent probe for detecting fluorinion and its synthesis method and uses UNIV SHANDONG NORMAL (CN) 2007-08-01 CN claimed
US-4072710-A FROM SILYL ESTER AND THIONYL CHLORIDE PALOMO COLL A L 1978-02-07 US claimed
EP-4083046-B1 METHOD FOR PREPARING HALOSILANE COMPOUNDS SHINETSU CHEMICAL CO (JP) 2025-03-26 EP disclosed
CN-118831596-A Hydrophobically modified ethylene oxychlorination catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-10-25 CN disclosed
US-11731992-B2 Method for preparing halosilane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-22 US disclosed
US-20220356195-A1 METHOD FOR PREPARING HALOSILANE COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-11-10 US disclosed
EP-4083046-A2 METHOD FOR PREPARING HALOSILANE COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-11-02 EP disclosed
WO-2021215106-A1 POLYORGANOSILSESQUIOXANE, MULTILAYER BODY AND SURFACE-COATED MOLDED BODY 株式会社ダイセル (JP) 2021-10-28 WO disclosed
EP-2128897-B1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LTD (JP) 2015-05-06 EP disclosed
US-8716209-B2 Agent for post-etch treatment of silicon dielectric film, method of manufacturing semiconductor device, and semiconductor device FUJITSU LIMITED (JP) 2014-05-06 US disclosed
CN-101007821-A Fluorescent probe for detecting fluorinion and its synthesis method and uses UNIV SHANDONG NORMAL (CN) 2007-08-01 CN disclosed
CN-1683355-A Process for preparing DL-nebivolol and its hydrochloride XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) 2005-10-19 CN disclosed
EP-0714898-B1 PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2001-11-14 EP disclosed
CN-1245807-A Preparation method of silicane whose alpha-position related to silicon atom possesses tertiary alkyl radical WACKER CHEMIE GMBH (DE) 2000-03-01 CN disclosed
US-5707997-A ANALGESICS OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1998-01-13 US disclosed
EP-0714898-A1 PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1996-06-05 EP disclosed
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed
US-4611063-A Silicon-bearing amides SANDOZ CORP. (US) 1986-09-09 US disclosed
US-4420475-A ANTICHOLESTEROL AGENTS, SILANATION SANDOZ, INC. (US) 1983-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356195-A1 METHOD FOR PREPARING HALOSILANE COMPOUNDS RAD52, RPS4X, RPSA TSHR 1081/4885LMNA 4602/4885TDP1 4638/4885
US-11731992-B2 Method for preparing halosilane compounds RAD52, RPS4X, RPSA TSHR 1081/4885LMNA 4602/4885TDP1 4638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.