SCHEMBL974669

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL974821	0.92	HRH3 (0.38)	HRH3BTKSMPD3ACKR3CHRNA7
	SCHEMBL973764	0.90	BTK (0.45)	HRH3BTKGLSACKR3CHRNA7
	SCHEMBL973310	0.90	TRPV1 (0.41)	CA12CA1CA2CA4CA7
	SCHEMBL973812	0.89	HRH3 (0.38)	HRH3BTKSMPD3ACKR3CHRNA7
	SCHEMBL974706	0.89	BTK (0.38)	HRH3CA12CA1CA2CA4
	SCHEMBL971211	0.89	CHRM5 (0.41)	BTK
	SCHEMBL973017	0.89	NAAA (0.46)	HRH3BTKSMPD3GLS
	SCHEMBL974236	0.87	BTK (0.38)	HRH3CA12CA1CA2CA4
	SCHEMBL974422	0.85	BTK (0.38)	HRH3BTKACKR3CHRNA7DRD2
	SCHEMBL975864	0.85	BTK (0.38)	HRH3CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.