Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.59 |
| ▸ | RARG | P13631 | 12/20 | 0.59 |
| ▸ | RARA | P10276 | 11/20 | 0.59 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.59 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.59 |
| ▸ | RXRA | P19793 | 4/20 | 0.56 |
| ▸ | RXRB | P28702 | 3/20 | 0.56 |
| ▸ | RXRG | P48443 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102425 | 0.83 | ALDH1A1 (0.58) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9746945 | 0.83 | RXRA (0.80) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8839076 | 0.81 | RXRA (0.71) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9746653 | 0.81 | RARB (0.57) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8839242 | 0.80 | RXRA (0.69) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8676840 | 0.78 | RXRB (0.71) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8839103 | 0.77 | RXRA (0.52) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8839146 | 0.76 | RXRA (0.67) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL5680238 | 0.76 | RXRA (0.81) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL2391376 | 0.75 | RARB (1.00) | RARBRARGRARACYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | claimed |
| US-4826969-A | SKIN AND EYE DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-05-02 | — | — | US | disclosed |