Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547407 | 0.86 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL3674655 | 0.86 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL19717843 | 0.86 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL2517738 | 0.84 | KDM4E (0.57) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL3676680 | 0.83 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL5054273 | 0.83 | FOLH1 (0.57) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL2571460 | 0.80 | PPARG (0.56) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| Sebacic Acid SCHEMBL7696353 | 0.79 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL9136787 | 0.78 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL28878425 | 0.78 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875283-B2 | A stent coated with hydrophobic polymer having water-labile bonds and strength to withstand forces of the vascular systems and also biodegrades on its surface rather than bulk erosion; mechanical properties; drug delivery; a polyester,-anhydride or -amide having the monomer, trimellitylimidotyrosine | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-01-25 | — | — | US | disclosed |
| US-20050232971-A1 | Biodegradable polymers for use with implantable medical devices | HOSSAINY SYED F | 2005-10-20 | — | — | US | disclosed |