Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554352 | 0.89 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL6836605 | 0.83 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| Azelaic Acid SCHEMBL7892389 | 0.81 | ALDH1A1 (0.56) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL28878425 | 0.79 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL9136787 | 0.79 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL974685 | 0.79 | KDM4E (0.46) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL17309756 | 0.78 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL17309764 | 0.78 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| Sebacic Acid SCHEMBL3897460 | 0.78 | KMT2A (0.67) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL17309763 | 0.78 | KDM4E (0.61) | KDM4EKMT2AMEN1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340501-B2 | Marinopyrrole derivatives as anticancer agents | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150080632-A1 | MARINOPYRROLE DERIVATIVES AS ANTICANCER AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-03-19 | — | — | US | disclosed |
| US-6342051-B1 | Treatment of anoxic tissue with angiogenesis-inducing implants | VITROPHAGE, INC. | 2002-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080632-A1 | MARINOPYRROLE DERIVATIVES AS ANTICANCER AGENTS | MAP2, MAP4, MDN1 | KDM4E 2582/4885KMT2A 1823/4885MEN1 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.