SCHEMBL3674655

SCHEMBL3674655

CCCCCCC(Oc1ccccc1C(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
RECQL P46063 1/20 0.56
ALDH1A1 P00352 4/20 0.54
CTRC Q99895 1/20 0.49
PPARG P37231 4/20 0.46
PTGES O14684 1/20 0.46
ALOX5 P09917 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
LMNA P02545 2/20 0.46
NR1I2 O75469 1/20 0.46
CHRM2 P08172 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADRA2A P08913 1/20 0.46
MAPT P10636 1/20 0.46
OPRK1 P41145 1/20 0.46
HTR2B P41595 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19717843 1.00 KDM4E (0.56) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL547407 1.00 KDM4E (0.56) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL2517738 0.99 KDM4E (0.57) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL3676680 0.94 KDM4E (0.58) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL30639267 0.90 CTRC (0.54) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL2571460 0.88 PPARG (0.56) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL6034422 0.86 SLC6A3 (0.47) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL6036084 0.86 KDM4E (0.53) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL6035267 0.86 KDM4E (0.53) KDM4EMEN1KMT2ARECQLALDH1A1
SCHEMBL974685 0.86 KDM4E (0.46) KDM4EMEN1KMT2ARECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1429606-B1 USE OF SALICYLIC ACID ESTERS AND ASSOCIATIONS THEREOF WITH ELICITINS IN THE PROTECTION OF PLANTS AGRONOMIQUE INST NAT RECH (FR) 2010-04-28 EP claimed
EP-1951790-A2 INITIATORS AND CROSSLINKABLE POLYMERIC MATERIALS A Enterprises, Inc. (US) 2008-08-06 EP disclosed
WO-2007081396-A9 INITIATORS AND CROSSLINKABLE POLYMERIC MATERIALS ENTPR INC A (US) 2007-09-07 WO disclosed
WO-2007081396-A2 INITIATORS AND CROSSLINKABLE POLYMERIC MATERIALS A ENTERPRISES, INC. (US) 2007-07-19 WO disclosed
WO-1998019626-A2 METHOD AND DEVICE FOR CONTINUOUS INTRALUMENAL DELIVERY OF BIOACTIVE SUBSTANCES LOCALMED, INC. (US) 1998-05-14 WO disclosed
US-5342348-A Stents having delivery matrices which provide for the controlled release of bioactive substances KAPLAN AARON V (US) 1994-08-30 US disclosed
EP-0605554-A1 OXIDISING COMPOSITIONS WARWICK INTERNATIONAL GROUP LIMITED(2660720) (GB) 1994-07-13 EP disclosed
WO-1994013268-A1 METHOD AND DEVICE FOR TREATING AND ENLARGING BODY LUMENS KAPLAN AARON V (US) 1994-06-23 WO disclosed
WO-1993006203-A1 OXIDISING COMPOSITIONS WARWICK INTERNATIONAL GROUP LTD. (GB) 1993-04-01 WO disclosed
EP-0368912-A4 POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES 1990-12-19 EP disclosed
EP-0368912-A1 POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES. MASSACHUSETTS INST TECHNOLOGY (US) 1990-05-23 EP disclosed
WO-1989000855-A1 POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-02-09 WO disclosed