Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149081 | 0.81 | ABCB1 (0.52) | AHRALOX5ABCB1GABRA1GABRB2 | |
| SCHEMBL29149110 | 0.81 | AHR (0.45) | AHRALOX5ABCB1BACE1HNF4A | |
| SCHEMBL31010871 | 0.80 | ALOX5 (0.63) | AHRALOX5ABCB1ACMSDESR2 | |
| SCHEMBL31555997 | 0.79 | NPC1 (0.55) | AHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8674451 | 0.76 | CA1 (0.44) | AHRABCB1GABRA1GABRB2HTT | |
| SCHEMBL21872091 | 0.76 | ESR2 (0.47) | AHRMEN1HTTKMT2AESR2 | |
| SCHEMBL38654768 | 0.75 | NR1H4 (0.57) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL17878569 | 0.75 | ALOX5 (0.57) | ALOX5HNF4AACMSDGABRA1GABRB2 | |
| SCHEMBL7418616 | 0.75 | BACE1 (0.47) | AHRALOX5ABCB1BACE1BCL2L1 | |
| SCHEMBL9496481 | 0.75 | BACE1 (0.52) | AHRALOX5ABCB1BACE1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |