Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646463 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPK1TDP1TSHRHPGD | |
| SCHEMBL9747334 | 0.81 | MAPT (0.48) | ALDH1A1TDP1KDM4EHPGDKMT2A | |
| SCHEMBL12170111 | 0.78 | MEN1 (0.48) | ALDH1A1S100A4TDP1TSHRCYP3A4 | |
| SCHEMBL11316899 | 0.77 | KDM4E (0.42) | ALDH1A1TSHRKDM4EHPGDKMT2A | |
| SCHEMBL8108179 | 0.76 | TDP1 (0.64) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL8689320 | 0.76 | TDP1 (0.64) | ALDH1A1TDP1TSHRCYP3A4ALOX15 | |
| SCHEMBL31168854 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRKDM4EHPGD | |
| SCHEMBL8115612 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRKDM4EHPGD | |
| SCHEMBL31632536 | 0.74 | ALDH1A1 (0.44) | ALDH1A1S100A4MAPK1TDP1CYP3A4 | |
| SCHEMBL7119411 | 0.74 | KDM4E (0.55) | ALDH1A1TSHRKDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |