Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869351 | 0.83 | TDP1 (0.50) | MAPTGAAKDM4EPOLBCTDSP1 | |
| SCHEMBL9747124 | 0.81 | ALDH1A1 (0.41) | MAPTGAAKDM4ETDP1ALDH1A1 | |
| SCHEMBL28215127 | 0.80 | TDP1 (0.56) | MAPTKDM4EPOLBCTDSP1TDP1 | |
| SCHEMBL28428409 | 0.78 | TDP1 (0.60) | GAAKDM4EPOLBCTDSP1TDP1 | |
| SCHEMBL835587 | 0.77 | MAPT (0.58) | MAPTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL13835525 | 0.75 | TDP1 (0.53) | MAPTGAAKDM4EPOLBCTDSP1 | |
| SCHEMBL8108179 | 0.74 | TDP1 (0.64) | GAAPOLBCTDSP1TDP1L3MBTL1 | |
| SCHEMBL104452 | 0.74 | PKM (0.59) | KDM4EPOLBCTDSP1TDP1L3MBTL1 | |
| SCHEMBL16955551 | 0.74 | TDP1 (0.50) | MAPTGAAKDM4EPOLBCTDSP1 | |
| SCHEMBL29740471 | 0.74 | PKM (0.59) | KDM4EPOLBCTDSP1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |