Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746782 | 0.88 | HCAR2 (0.33) | — | |
| SCHEMBL9747650 | 0.80 | — | — | |
| SCHEMBL824893 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL187851 | 0.74 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10388018 | 0.72 | EPHX1 (0.44) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10863228 | 0.72 | ALDH1A1 (0.31) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6493221 | 0.72 | CYP1A2 (0.41) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1088906 | 0.72 | HMGCR (0.40) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL126072 | 0.71 | — | — | |
| SCHEMBL10163042 | 0.71 | EPHX2 (0.38) | ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204285-B1 | IMIDAZOHETEROCYCLIC COMPOUNDS PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4725601-A | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0204285-A1 | Imidazoheterocyclic compounds processes for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-10 | — | — | EP | disclosed |