Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824893 | 0.83 | ALDH1A1 (0.40) | CYP1A2ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL17188567 | 0.83 | — | — | |
| SCHEMBL187851 | 0.81 | ALDH1A1 (0.39) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL1088906 | 0.79 | HMGCR (0.40) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL126072 | 0.78 | — | — | |
| SCHEMBL1089589 | 0.78 | PTPN7 (0.46) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL10163042 | 0.78 | EPHX2 (0.38) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL18446 | 0.77 | ALDH1A1 (0.53) | CYP1A2ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1101207 | 0.76 | PTPN7 (0.48) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL14873844 | 0.76 | PTPN7 (0.48) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951863-B2 | Pyridoarylphenly oxazolidinone antibacterials, and related compositions and methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| US-20030176422-A1 | For therapy of bacterial infections in humans and animals | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176422-A1 | For therapy of bacterial infections in humans and animals | OXA1L, PIGS, NDUFS3 | CYP1A2 1306/4885ALOX15 1775/4885ALDH1A1 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.