Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207540 | 0.90 | CYSLTR2 (0.40) | PLA2G2ACYSLTR2CYSLTR1 | |
| SCHEMBL9207543 | 0.90 | CYSLTR2 (0.40) | PLA2G2ACYSLTR2CYSLTR1 | |
| SCHEMBL9209485 | 0.87 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1 | |
| SCHEMBL9209480 | 0.87 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1 | |
| SCHEMBL9746290 | 0.86 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9203800 | 0.82 | PLA2G2A (0.50) | PLA2G2A | |
| SCHEMBL9203804 | 0.82 | PLA2G2A (0.50) | PLA2G2A | |
| SCHEMBL9747322 | 0.79 | — | — | |
| SCHEMBL9208190 | 0.79 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1 | |
| SCHEMBL9208205 | 0.79 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104882-A | Leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1992-04-14 | — | — | US | disclosed |