Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207540 | 1.00 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1PLA2G2A | |
| SCHEMBL9747317 | 0.90 | ALDH1A1 (0.37) | CYSLTR2CYSLTR1PLA2G2A | |
| SCHEMBL9209485 | 0.90 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1 | |
| SCHEMBL9209480 | 0.90 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1 | |
| SCHEMBL9203199 | 0.84 | CYSLTR1 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL9203196 | 0.84 | CYSLTR1 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL9203800 | 0.83 | PLA2G2A (0.50) | PLA2G2A | |
| SCHEMBL9203804 | 0.83 | PLA2G2A (0.50) | PLA2G2A | |
| SCHEMBL9747322 | 0.83 | — | — | |
| SCHEMBL9208190 | 0.83 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399818-B1 | Diarylstyrylquinoline diacids | MERCK FROSST CANADA INC (CA) | 1995-08-16 | — | — | EP | disclosed |
| US-5204358-A | Antiallergens; antiinflammatory agents; treatment of asthma, rhinitis, bronchitis and skin diseases | MERCK FROSST CANADA, INC. (CA) | 1993-04-20 | — | — | US | disclosed |
| EP-0399818-A1 | Diarylstyrylquinoline diacids | MERCK FROSST CANADA INC. (CA) | 1990-11-28 | — | — | EP | disclosed |