SCHEMBL9747622

SCHEMBL9747622

C=C(C(=O)Oc1ccccc1)C(Cl)CCl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
ATM Q13315 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
CYP19A1 P11511 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
RNF4 P78317 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
SLC1A3 P43003 1/20 0.33
CASP1 P29466 1/20 0.33
NSD2 O96028 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696384 0.82 ELANE (0.45) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL9747672 0.79 ELANE (0.42) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL10399716 0.79 ATM (0.46) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL9746065 0.75 ELANE (0.45) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL9746928 0.75 ELANE (0.45) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL8080216 0.75 ELANE (0.49) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL9745967 0.75 ELANE (0.45) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL9745709 0.75 ELANE (0.41) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL5081333 0.74 ELANE (0.47) ELANEATML3MBTL1TDP1ALOX15
SCHEMBL9745779 0.73 ELANE (0.41) ELANEATML3MBTL1TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed