Acrylonitrile

Acrylonitrile

SCHEMBL9747659

C=C(C=C(C)C(=O)O)C(=O)OCC.C=CC#N

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TSHR P16473 1/20 0.45
CYP2C9 P11712 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35
GLO1 Q04760 1/20 0.35
CYP2D6 P10635 2/20 0.33
PTP4A1 Q93096 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 5/20 0.33
MAPT P10636 4/20 0.33
MEN1 O00255 4/20 0.33
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
GAA P10253 2/20 0.32
LMNA P02545 2/20 0.32
THRB P10828 2/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432150 0.89 NPSR1 (0.42) ALDH1A1TSHRCYP2C9NPSR1GLO1
Ammonia Solution, Strong SCHEMBL15128898 0.87 NPSR1 (0.41) ALDH1A1TSHRNPSR1GLO1CYP2D6
Acrylonitrile SCHEMBL9330815 0.86 TSHR (0.42) ALDH1A1TSHRCYP2C9CYP2C19KDM4E
Acrylic Acid SCHEMBL3651329 0.86 NPSR1 (0.38) ALDH1A1TSHRNPSR1GLO1CYP2D6
Methacrylic Acid SCHEMBL9069461 0.85 NPSR1 (0.40) ALDH1A1TSHRNPSR1GLO1CYP2D6
SCHEMBL10336736 0.84 THRB (0.44) ALDH1A1TSHRNPSR1GLO1CYP2D6
Acrylonitrile SCHEMBL6554745 0.83 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL9301639 0.81 NPSR1 (0.37) ALDH1A1TSHRNPSR1GLO1CYP2D6
Acrylic Acid Methyl Ester SCHEMBL8607329 0.81 NPSR1 (0.38) ALDH1A1TSHRNPSR1GLO1CYP2D6
SCHEMBL195064 0.80 ALDH1A1 (0.47) ALDH1A1TSHRNPSR1GLO1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5106724-A High speed, odorless KONICA CORPORATION (JP) 1992-04-21 US disclosed
US-4467027-A O-QUINONEDIAZIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-08-21 US disclosed