Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
| ▸ | CCR4 | P51679 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14370854 | 0.84 | KDM4E (0.50) | CCR1CCR2CCR4CYP3A4CYP2C9 | |
| SCHEMBL7445529 | 0.84 | CCR1 (0.50) | CCR1CCR2CCR4CYP19A1MEN1 | |
| SCHEMBL9202589 | 0.84 | BRD4 (0.51) | CCR1CCR2CCR4CYP19A1MEN1 | |
| SCHEMBL8936736 | 0.81 | CYP19A1 (0.53) | CCR1CCR2CCR4CYP3A4CYP2C9 | |
| SCHEMBL3158915 | 0.81 | CYP19A1 (0.50) | CCR1CCR2CCR4CYP19A1KMT2A | |
| SCHEMBL940881 | 0.79 | CYP19A1 (0.62) | CCR1CCR2CCR4CYP19A1MEN1 | |
| SCHEMBL2353053 | 0.78 | KMT2A (0.49) | CCR1CCR2CCR4CYP3A4CYP2C9 | |
| SCHEMBL10510964 | 0.78 | MEN1 (0.55) | CCR1CCR2CCR4CYP3A4CYP2C9 | |
| SCHEMBL7450404 | 0.78 | CCR1 (0.51) | CCR1CCR2CCR4CYP19A1MEN1 | |
| SCHEMBL10809801 | 0.78 | LMNA (0.54) | CCR1CCR2CCR4CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100890-A | Antidepressants, Fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0218118-B1 | ARYLMETHYL AZOLES AND THEIR SALTS, METHOD FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| US-5023357-A | Arylmethylazole preparation processes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |
| US-4876354-A | FUNGICIDES, ANTIDEPRESSANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| EP-0218118-A1 | Arylmethyl azoles and their salts, method for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-15 | — | — | EP | disclosed |