Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9793239 | 1.00 | MAPK1 (0.44) | MAPK1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL5933815 | 1.00 | MAPK1 (0.44) | MAPK1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL4919102 | 1.00 | MAPK1 (0.44) | MAPK1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL28237049 | 0.95 | MAPK1 (0.40) | MAPK1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL5787261 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL11577435 | 0.89 | SLC34A1 (0.39) | MAPK1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL1311 | 0.88 | — | — | |
| Phosphoric Acid SCHEMBL5923091 | 0.88 | LMNA (0.46) | MAPK1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL262002 | 0.88 | LMNA (0.46) | MAPK1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL74097 | 0.88 | SLC34A1 (0.46) | LMNASLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214507-B1 | OUTDOOR FILMS STABILIZED AGAINST CHEMICAL ATTACK | AMERICAN CYANAMID COMPANY (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0214507-A2 | Outdoor films stabilized against chemical attack | AMERICAN CYANAMID COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |