Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.48 |
| ▸ | FFAR3 | O14843 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31195898 | 0.86 | HDAC3 (0.48) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL8599484 | 0.84 | FNTA (0.52) | ALDH1A1CES2CES1FNTAFNTB | |
| SCHEMBL8599489 | 0.84 | FNTA (0.52) | ALDH1A1CES2CES1FNTAFNTB | |
| SCHEMBL797279 | 0.84 | GRIK1 (0.41) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL554603 | 0.83 | HDAC3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL184432 | 0.83 | HDAC3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL554602 | 0.83 | HDAC3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10560641 | 0.82 | GRIK1 (0.47) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL28065698 | 0.82 | FFAR3 (0.43) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL7871455 | 0.81 | FNTA (0.64) | ALDH1A1CES2CES1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014186292-A1 | DETECTION IN THERMOPLASTICS | DANES JEFFREY E (US) | 2014-11-20 | — | — | WO | disclosed |
| EP-0515506-A1 | IMPROVEMENTS IN THE SPECIFICITY AND CONVENIENCE OF THE POLYMERASE CHAIN REACTION | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012342-A1 | IMPROVEMENTS IN THE SPECIFICITY AND CONVENIENCE OF THE POLYMERASE CHAIN REACTION | F. HOFFMANN-LA ROCHE AG (CH) | 1991-08-22 | — | — | WO | disclosed |