Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176981 | 0.88 | SIGMAR1 (0.45) | KCNH2SIGMAR1PTGESALOX5PPARG | |
| SCHEMBL6251205 | 0.81 | CSNK1E (0.45) | PLA2G10PLA2G2ACTSK | |
| SCHEMBL292546 | 0.81 | SIGMAR1 (0.41) | KCNH2SIGMAR1PPARGIDO1 | |
| SCHEMBL18511763 | 0.81 | PLA2G2A (0.54) | KCNH2SIGMAR1PLA2G10PLA2G1BPLA2G2A | |
| SCHEMBL18511748 | 0.81 | PLA2G2A (0.54) | KCNH2SIGMAR1PLA2G10PLA2G1BPLA2G2A | |
| SCHEMBL18512611 | 0.81 | PLA2G2A (0.54) | KCNH2SIGMAR1PLA2G10PLA2G1BPLA2G2A | |
| SCHEMBL18512633 | 0.81 | PLA2G2A (0.54) | KCNH2SIGMAR1PLA2G10PLA2G1BPLA2G2A | |
| SCHEMBL18512617 | 0.81 | PLA2G2A (0.54) | KCNH2SIGMAR1PLA2G10PLA2G1BPLA2G2A | |
| SCHEMBL5606109 | 0.79 | PLA2G2A (0.50) | PLA2G10PLA2G1BPLA2G2APLA2G5 | |
| SCHEMBL5605740 | 0.79 | PLA2G2A (0.50) | PLA2G10PLA2G1BPLA2G2APLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |