Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 7/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.50 |
| ▸ | HTR3B | O95264 | 4/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747490 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9748207 | 0.86 | HTR3A (0.53) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9747336 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9747774 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9748440 | 0.84 | HTR3A (0.49) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9748168 | 0.84 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9531363 | 0.82 | HTR3A (0.56) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9531232 | 0.82 | HTR3A (0.53) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9747852 | 0.81 | MEN1 (0.52) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL9748364 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254584-B1 | AZABICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1992-10-07 | — | — | EP | claimed |
| US-4822795-A | Pharmaceutically useful esters and amides | BEECHAM GROPUP P.L.C. (GB) | 1989-04-18 | — | — | US | claimed |
| EP-0254584-A2 | Azabicyclic compounds, process for their preparation, and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1988-01-27 | — | — | EP | claimed |
| EP-0254584-B1 | AZABICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1992-10-07 | — | — | EP | disclosed |
| US-4822795-A | Pharmaceutically useful esters and amides | BEECHAM GROPUP P.L.C. (GB) | 1989-04-18 | — | — | US | disclosed |