SCHEMBL9748319

SCHEMBL9748319

O=c1oc2c(O)c(O)ccc2c2cc(O)cc(O)c12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP1A1 P05023 2/20 0.61
ATP1B1 P05026 2/20 0.61
ATP1A3 P13637 2/20 0.61
ATP1B2 P14415 2/20 0.61
ATP1A2 P50993 2/20 0.61
ATP1B3 P54709 2/20 0.61
FXYD2 P54710 2/20 0.61
ATP1A4 Q13733 2/20 0.61
ACE P12821 2/20 0.61
PKLR P30613 2/20 0.61
GALNT2 Q10471 2/20 0.61
GALNT1 Q10472 1/20 0.61
GALNT3 Q14435 1/20 0.61
GALNT10 Q86SR1 1/20 0.61
GALNT13 Q8IUC8 1/20 0.61
GALNT6 Q8NCL4 1/20 0.61
GALNT14 Q96FL9 1/20 0.61
ESR1 P03372 7/20 0.53
ESR2 Q92731 7/20 0.53
MET P08581 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21517158 0.87 ATP1A1 (0.61) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL7984298 0.81 ESR2 (0.75) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL30436568 0.76 ATP1A1 (1.00) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL2313484 0.76 ATP1A1 (1.00) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL29370098 0.76 PKLR (1.00) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL7980209 0.76 PKLR (1.00) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL25153256 0.75 PDE2A (0.67) PKLRESR1ESR2CSNK2A1CLK2
SCHEMBL28899964 0.75 CLK2 (0.64) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL7987277 0.73 ESR2 (0.70) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL2357304 0.72 PKLR (0.68) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104894-A Ellagic acid analogues UNIVERSITY OF GUELPH (CA) 1992-04-14 US claimed