Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501701 | 0.77 | SIGMAR1 (0.43) | SIGMAR1KDM1AMAOBTSHRALDH1A1 | |
| SCHEMBL3225297 | 0.75 | SIGMAR1 (0.35) | SIGMAR1KDM1AMAOBTSHRALDH1A1 | |
| SCHEMBL19130507 | 0.75 | SIGMAR1 (0.41) | SIGMAR1KDM1AMAOBTSHRALDH1A1 | |
| SCHEMBL4736099 | 0.75 | KDM1A (0.42) | SIGMAR1KDM1AMAOBTSHRALDH1A1 | |
| SCHEMBL28922175 | 0.75 | SIGMAR1 (0.41) | SIGMAR1KDM1AMAOBALDH1A1TP53 | |
| SCHEMBL4734271 | 0.75 | KDM1A (0.42) | SIGMAR1KDM1AMAOBTSHRALDH1A1 | |
| SCHEMBL3231447 | 0.74 | SIGMAR1 (0.34) | SIGMAR1HTR2A | |
| SCHEMBL9570551 | 0.72 | SIGMAR1 (0.43) | SIGMAR1KDM1AMAOBTSHRALDH1A1 | |
| SCHEMBL9240715 | 0.72 | KDM1A (0.40) | SIGMAR1KDM1AMAOBTSHRALDH1A1 | |
| SCHEMBL3227098 | 0.72 | SIGMAR1 (0.38) | SIGMAR1KDM1AMAOBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |