Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20999343 | 0.97 | LOXL2 (0.72) | LOXL2TSHRMAOBMAOATAAR1 | |
| Benzylamine SCHEMBL23044693 | 0.94 | LOXL2 (0.78) | LOXL2TSHRMAOBMAOATAAR1 | |
| Benzylamine SCHEMBL5481672 | 0.88 | LOXL2 (1.00) | LOXL2TSHRMAOBMAOATAAR1 | |
| Benzylamine SCHEMBL10707644 | 0.88 | LOXL2 (1.00) | LOXL2TSHRMAOBMAOATAAR1 | |
| Benzylamine SCHEMBL1331207 | 0.88 | — | — | |
| SCHEMBL19242392 | 0.88 | LOXL2 (1.00) | LOXL2TSHRMAOBMAOATAAR1 | |
| Benzylamine SCHEMBL373 | 0.88 | — | — | |
| Benzylamine SCHEMBL8751247 | 0.85 | — | — | |
| Benzylamine SCHEMBL10738289 | 0.85 | LOXL2 (0.93) | LOXL2TSHRMAOBMAOATAAR1 | |
| Benzylamine SCHEMBL465924 | 0.85 | LOXL2 (0.93) | LOXL2TSHRMAOBMAOATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283757-B1 | AM IMPROVED PROCESS FOR POLYMERIC MDA, RECYCLE OF FINISHED POLYMERIC MDA | THE DOW CHEMICAL COMPANY (US) | 1992-01-08 | — | — | EP | disclosed |
| US-4792624-A | POLYMETHYLENE POLYPHENYL POLYAMINES | THE DOW CHEMICAL COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0283757-A1 | Am improved process for polymeric MDA, recycle of finished polymeric MDA | THE DOW CHEMICAL COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0109931-A2 | Process for the preparation of polyaryl amines showing methylene bridges | ELPROCHINE AG (CH) | 1984-05-30 | — | — | EP | disclosed |
| US-4294987-A | ACID CATALYST | THE UPJOHN COMPANY (US) | 1981-10-13 | — | — | US | disclosed |
| US-3931215-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |