Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CPA1 | P15085 | 7/20 | 0.59 |
| ▸ | CPA3 | P15088 | 3/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.59 |
| ▸ | MME | P08473 | 3/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252900 | 1.00 | CYP1A2 (0.68) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL9007628 | 1.00 | CYP1A2 (0.68) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL5096045 | 0.86 | PTGS2 (0.51) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL8144720 | 0.86 | CYP1A2 (0.53) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL2065619 | 0.86 | CYP1A2 (0.53) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL2361534 | 0.86 | CYP1A2 (0.53) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL11324047 | 0.86 | CYP1A2 (0.53) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL5966473 | 0.85 | PPARG (0.58) | CYP1A2 | |
| SCHEMBL9647546 | 0.85 | SLC1A1 (0.77) | CYP1A2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8301284 | 0.84 | PPARG (0.48) | CYP1A2CPA1CPA3MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-02-18 | — | — | US | disclosed |
| US-8530456-B2 | Sonic hedgehog modulators | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-09-10 | — | — | US | disclosed |
| EP-1296927-B1 | PREPARATION OF (R)-2-ALKYL-3-PHENYLPROPIONIC ACIDS | NOVARTIS AG (CH) | 2012-02-22 | — | — | EP | disclosed |
| CN-100482632-C | Preparation of (R)-2-alkyl-3-phenylpropionic acids | SPEEDEL PHARMA AG (CH) | 2009-04-29 | — | — | CN | disclosed |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | PHOENIX CHEMICALS LTD. (GB) | 2008-10-02 | — | — | US | disclosed |
| US-20080171892-A1 | Method for Producing Optically Active 3-Phenylpropionic Acid Derivatives and Follow-On Products of the Latter | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-17 | — | — | US | disclosed |
| EP-1838654-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | Phoenix Chemicals Limited (GB) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006075177-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
| US-6683206-B2 | STEREOSELECTIVE ADDITION TO BENZALDEHYDES; REGIOSELECTIVE ELIMINATION TO FORM 3-R-2-R3-PROPENIC ACID ESTERS; HYDROLYSIS; HYDROGENATION USING RUTHENIUM, RHODIUM OR IRIDIUM CATALYST | SPEEDEL PHARMA AG (CH) | 2004-01-27 | — | — | US | disclosed |
| US-6683206-B2 | STEREOSELECTIVE ADDITION TO BENZALDEHYDES; REGIOSELECTIVE ELIMINATION TO FORM 3-R-2-R3-PROPENIC ACID ESTERS; HYDROLYSIS; HYDROGENATION USING RUTHENIUM, RHODIUM OR IRIDIUM CATALYST | SPEEDEL PHARMA AG (CH) | 2004-01-27 | — | — | US | disclosed |
| CN-1440379-A | Preparation of -2-alkyl-3-phenylpropionic acid | SPEEDEL PHARMA AG (CH) | 2003-09-03 | — | — | CN | disclosed |
| US-20030139625-A1 | Preparation of (r -2-alkyl-3-phenylpropionic acids | SPEEDEL PHARMA AG (CH) | 2003-07-24 | — | — | US | disclosed |
| EP-1296927-A1 | PREPARATION OF (R)-2-ALKYL-3-PHENYLPROPIONIC ACIDS | Speedel Pharma AG (CH) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002500-A1 | PREPARATION OF (R)-2-ALKYL-3-PHENYLPROPIONIC ACIDS | SPEEDEL PHARMA AG (CH) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139625-A1 | Preparation of (r -2-alkyl-3-phenylpropionic acids | PCCA, APEH, ALDH1A1 | CYP1A2 141/4885CPA1 72/4885CPA3 221/4885 |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | AS3MT, PPA1, AGPS | CYP1A2 152/4885CPA1 2524/4885CPA3 4523/4885 |
| US-20080171892-A1 | Method for Producing Optically Active 3-Phenylpropionic Acid Derivatives and Follow-On Products of the Latter | ALDH1A2, ALDH1A3, PCCA | CYP1A2 160/4885CPA1 731/4885CPA3 1508/4885 |
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | SHH, GLI1, SMO | CYP1A2 4873/4885CPA1 3702/4885CPA3 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.