Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CPA1 | P15085 | 7/20 | 0.59 |
| ▸ | CPA3 | P15088 | 3/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.59 |
| ▸ | MME | P08473 | 3/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629350 | 1.00 | CYP1A2 (0.68) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL9007628 | 1.00 | CYP1A2 (0.68) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL5096045 | 0.86 | PTGS2 (0.51) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL11324047 | 0.86 | CYP1A2 (0.53) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL2065619 | 0.86 | CYP1A2 (0.53) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL2361534 | 0.86 | CYP1A2 (0.53) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL8144720 | 0.86 | CYP1A2 (0.53) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL5966473 | 0.85 | PPARG (0.58) | CYP1A2 | |
| SCHEMBL9647546 | 0.85 | SLC1A1 (0.77) | CYP1A2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8301284 | 0.84 | PPARG (0.48) | CYP1A2CPA1CPA3MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832923-A1 | Polyamide-acrylonitrile butadiene blends with reduced gel and antigel agent | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-02-18 | — | — | US | disclosed |
| US-8530456-B2 | Sonic hedgehog modulators | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-09-10 | — | — | US | disclosed |
| US-8470763-B2 | Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2013-06-25 | — | — | US | disclosed |
| US-8470763-B2 | Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2013-06-25 | — | — | US | disclosed |
| EP-1948643-B1 | 3-ALKYL-5- (4-ALKYL-5-OXO-TETRAHYDROFURAN-2-YL) PYRROLIDIN-2-ONE DERIVATIVES AS INTERMEDIATES IN THE SYNTHESIS OF RENIN INHIBITORS | NOVARTIS AG (CH) | 2013-06-05 | — | — | EP | disclosed |
| US-8338620-B2 | Methods for the production of C-8 lactam lactone compounds | NOVARTIS AG (CH) | 2012-12-25 | — | — | US | disclosed |
| US-8198465-B2 | 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors | NOVARTIS AG (CH) | 2012-06-12 | — | — | US | disclosed |
| EP-1296927-B1 | PREPARATION OF (R)-2-ALKYL-3-PHENYLPROPIONIC ACIDS | NOVARTIS AG (CH) | 2012-02-22 | — | — | EP | disclosed |
| US-8088955-B2 | Alpha-substituted α,β-unsaturated E- or Z-aldehydes, use thereof, and processes for their preparation α,β | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) | 2012-01-03 | — | — | US | disclosed |
| US-20030139625-A1 | Preparation of (r -2-alkyl-3-phenylpropionic acids | SPEEDEL PHARMA AG (CH) | 2003-07-24 | — | — | US | disclosed |
| EP-1296912-A1 | PROCESS FOR THE PREPARATION OF (R)-2-ALKYL-3-PHENYL-1-PROPANOLS | Speedel Pharma AG (CH) | 2003-04-02 | — | — | EP | disclosed |
| EP-1296927-A1 | PREPARATION OF (R)-2-ALKYL-3-PHENYLPROPIONIC ACIDS | Speedel Pharma AG (CH) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002500-A1 | PREPARATION OF (R)-2-ALKYL-3-PHENYLPROPIONIC ACIDS | SPEEDEL PHARMA AG (CH) | 2002-01-10 | — | — | WO | disclosed |
| WO-2002002487-A1 | PROCESS FOR THE PREPARATION OF (R)-2-ALKYL-3-PHENYL-1-PROPANOLS | SPEEDEL PHARMA AG (CH) | 2002-01-10 | — | — | WO | disclosed |
| US-5852086-A | Polyamide-acrylonitrile butadiene blends with reduced gel and antigel agent | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0832923-A1 | Polyamide-acrylonitrile butadiene blends with reduced gel and antigel agent | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5569762-A | Asymmetric synthesis of intermediates for retroviral protease inhibitor compounds | AMERICAN CYANAMID COMPANY (US) | 1996-10-29 | — | — | US | disclosed |
| US-5428167-A | Asymmetric synthesis of intermediates for retroviral protease inhibitor compounds | AMERICAN CYANAMID COMPANY (US) | 1995-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139625-A1 | Preparation of (r -2-alkyl-3-phenylpropionic acids | PCCA, APEH, ALDH1A1 | CYP1A2 141/4885CPA1 72/4885CPA3 221/4885 |
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | SHH, GLI1, SMO | CYP1A2 4873/4885CPA1 3702/4885CPA3 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.