Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922738 | 0.85 | KMT2A (0.55) | KMT2APOLBALDH1A1HPGDKDM4E | |
| SCHEMBL9163650 | 0.85 | ALDH1A1 (0.38) | KMT2APOLBALDH1A1HPGDKDM4E | |
| SCHEMBL1768506 | 0.82 | STAT3 (0.55) | KMT2AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9776043 | 0.82 | KMT2A (0.40) | KMT2APOLBALDH1A1HPGDKDM4E | |
| SCHEMBL29576801 | 0.81 | KMT2A (0.56) | KMT2APOLBALDH1A1HPGDKDM4E | |
| SCHEMBL11402926 | 0.81 | KMT2A (0.56) | KMT2APOLBALDH1A1HPGDKDM4E | |
| SCHEMBL11065418 | 0.81 | KMT2A (0.61) | KMT2APOLBALDH1A1HPGDKDM4E | |
| SCHEMBL8041564 | 0.80 | POLB (0.69) | KMT2APOLBALDH1A1HPGDKDM4E | |
| SCHEMBL10923394 | 0.80 | KMT2A (0.55) | KMT2APOLBALDH1A1HPGDKDM4E | |
| SCHEMBL29823822 | 0.80 | POLB (0.69) | KMT2APOLBALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248072-B1 | AMIFLOXACINE INTERMEDIATE | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-03-18 | — | — | EP | disclosed |
| US-4871849-A | 6-FLUORO-7-(PIPERAZINYL OR 4-METHYLPIPERAZINYL) SUBSTITUTED AN TIBACTERIAL AGENTS; NOVEL 3,4-O-BORON DERIVATIVE INTERMEDIATES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1989-10-03 | — | — | US | disclosed |
| US-4806645-A | Boric anhydrides of 6-fluoro-7-chloro-1-methylamino-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1989-02-21 | — | — | US | disclosed |
| EP-0248876-A1 | PROCESS FOR THE PREPARATION OF 1-METHYLAMINO-QUINOLINE-CARBOXYLIC ACID DERIVATIVES. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1987-12-16 | — | — | EP | disclosed |
| EP-0248072-A1 | AMIFLOXACINE INTERMEDIATE. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1987-12-09 | — | — | EP | disclosed |
| WO-1987003594-A1 | AMIFLOXACINE INTERMEDIATE | CHINOIN GYÓGYSZERRÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1987-06-18 | — | — | WO | disclosed |
| WO-1987003586-A1 | PROCESS FOR THE PREPARATION OF 1-METHYLAMINO-QUINOLINE-CARBOXYLIC ACID DERIVATIVES | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1987-06-18 | — | — | WO | disclosed |
| EP-0090424-B1 | NEW QUINOLONE COMPOUNDS AND PREPARATION THEREOF | STERLING DRUG INC. (US) | 1986-05-28 | — | — | EP | disclosed |
| US-4499091-A | 1-Amino (or substituted amino)-1,4-dihydro-4-oxo-6-fluoro-7-heterylquinoline-3-carboxylic acids and their use as antibacterial agents | STERLING DRUG INC. (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0090424-A1 | New quinolone compounds and preparation thereof | STERLING DRUG INC. (US) | 1983-10-05 | — | — | EP | disclosed |