SCHEMBL9748614

SCHEMBL9748614

CCC(C)(C=O)Cc1cccc(C)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.41
ACHE P22303 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
IDO1 P14902 2/20 0.40
CTBP2 P56545 1/20 0.40
GPR84 Q9NQS5 1/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
DAO P14920 1/20 0.36
HRH3 Q9Y5N1 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9749907 0.84 CYP3A4 (0.37) MEN1KMT2A
SCHEMBL1697989 0.81 MEN1 (0.46) TAAR1ACHEMAOAMAOBIDO1
SCHEMBL29845719 0.81 MEN1 (0.46) TAAR1ACHEMAOAMAOBIDO1
SCHEMBL6792841 0.80 SLC6A2 (0.47) TAAR1
SCHEMBL758533 0.74 ACHE (0.55) TAAR1ACHEMAOAMAOBIDO1
SCHEMBL29941639 0.74 ACHE (0.55) TAAR1ACHEMAOAMAOBIDO1
SCHEMBL9748823 0.74 ACHE (0.44) TAAR1ACHEMAOBIDO1CTBP2
SCHEMBL2260409 0.73 TAAR1 (0.41) TAAR1ACHEMAOAMAOBIDO1
SCHEMBL16266171 0.72 TAAR1 (0.43) TAAR1ACHEIDO1CTBP2POLB
SCHEMBL6795617 0.72 TSHR (0.49) ACHEGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0217159-B1 ALDEHYDES, ACETALS, ALCOHOLS AND ETHERS WITH 3-METHYL OR 3,5-DIMETHYLBENZYL GROUPS, THEIR PREPARATION AND THEIR USE AS FRAGRANCE COMPOUNDS Consortium für elektrochemische Industrie GmbH (DE) 1992-01-02 EP disclosed
US-4710316-A Aldehydes, acetals, alcohols and ethers having 3-methyl- or 3,5-dimethyl-benzyl groups, their manufacture and perfume materials containing same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1987-12-01 US disclosed
EP-0217159-A2 Aldehydes, acetals, alcohols and ethers with 3-methyl or 3,5-dimethylbenzyl groups, their preparation and their use as fragrance compounds Consortium für elektrochemische Industrie GmbH (DE) 1987-04-08 EP disclosed