SCHEMBL2260409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL563643	0.84	TACR1 (0.34)	ALDH1A1LMNACYP2D6MEN1KMT2A
	SCHEMBL165251	0.80	LMNA (0.59)	TAAR1ALDH1A1LMNACYP2D6MEN1
	SCHEMBL1719722	0.80	HTR2A (0.46)	TAAR1MAOBIDO1POLBALDH1A1
	SCHEMBL29845719	0.77	MEN1 (0.46)	TAAR1ACHEMAOAMAOBIDO1
	SCHEMBL1697989	0.77	MEN1 (0.46)	TAAR1ACHEMAOAMAOBIDO1
	SCHEMBL6434210	0.75	CYP1A2 (0.46)	CYP2D6
	SCHEMBL564806	0.74	HDAC3 (0.39)	MMP13
	SCHEMBL29941639	0.74	ACHE (0.55)	TAAR1ACHEMAOAMAOBIDO1
	SCHEMBL758533	0.74	ACHE (0.55)	TAAR1ACHEMAOAMAOBIDO1
	SCHEMBL9748614	0.73	TAAR1 (0.41)	TAAR1ACHEMAOAMAOBIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.